Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

Actor in a Comedy Series: Jeffrey Tambor, “Transparent”
12. Scientists modify photosynthesis to boost crop yield
它是一种受谅解和制度制约的权力争斗。
[ri'f?:m]
玛丽?芭拉从通用汽车的第三把交椅升至第一把交椅,获得首席执行官提名,这一路上她突破了好几个历史性障碍。一方面,通过任命一位非执行主席掌管董事会,她能更容易打开工作局面;但另一方面,由于一位对手接手了她以前的职责,她现在的工作又变得更棘手了。她是二十年来首位掌管公司的产品工程师,各种建议势必将纷至沓来,令人应接不暇。这些建议小到新皮卡上的空调出风口,大到别克(Buick)和雪佛兰(Chevrolet)这些品牌的前景,无所不包。
The London school’s MBA is ranked first in Europe, its EMBA programme, delivered jointly with Columbia Business School in the US, is ranked third and its MiM programme is in the top 10 on its first participation. The MiM ranking was the last missing piece for LBS to come first in Europe.
9.忠诚待人
Set between the events of Star Wars Episode III and IV, Rogue One will most likely be about bounty hunters who set out to steal the Death Star plans. We're not exactly sure of the plot.
移动端取代网页端。
If the oldest man ever elected president can “tweet like a kindergartner,” why not flip the script and see if a youngster can be elected to office and govern wisely?
Speaking of his desire to make their relationship to be 'official', Lagerfeld once said: 'There is no marriage, yet, for human beings and animals… I never thought that I would fall in love like this with a cat.
Amazon founder Jeff Bezos rose to No. 3 on the list for the first time, thanks to the jump in in Amazon shares, which boosted his net worth to $72.8 billion.
《Chandelier》的视频点击量已突破7.12亿,是YouTube点击量最高的MV排行榜上的第17名。
We will step up the development of public facilities in rural areas.
伊朗持不同政见电影人扮演一个几乎不合格的德黑兰出租车司机,带来一部狡猾的伪纪录片,深入探讨电影的悖论,以及专制统治下日常生活中的矛盾。
8. “Mad Max: Fury Road”(George Miller)
“…started swearing during the interview.”
A Times reporter, Denise Grady, went inside an operating room to observe an experimental technique to treat severe spina bifida in a 24-week-old fetus. The doctors performing the surgery hope it will result in superior outcomes for children born with the disorder. Their first 28 surgeries have seen good results so far. Jan. 14 is the due date for the mother who was the subject of the article.
4. 詹妮弗-安妮斯顿 2100万美元
2010年的头号热门搜索问题是“如何打领带”,其次是“如何减肥”、“如何接吻”以及“如何写简历”。
Consumers in many parts of the world have a preference for buying local which has helped boost the value of local brands.
但是这些烂队中没有一支队伍有摆烂的打算。他们这样打算合适吗?为球队着想,他们应该摆烂吗?
新年已至,让我们在此总结一下石油市场形势。实际情况表明,2014年对石油市场来说非常重要——油价在短短六个月内下降了一半。
Meanwhile, La Rochelle Business School dropped 12 places to 60 having been last year’s highest climber.
assured


你花在上网上的时间多于你工作的时间
这份排行榜衡量的是商学院研究生课程的质量和广度。它基于相关商学院在英国《金融时报》每年发布的4个主要榜单上的表现:MBA、EMBA、管理硕士和高管教育。只有参与所有这4项排名的商学院才有资格获得满分。
爆破公司总指挥贾永胜告诉中国国营电视台CCTV说:像这样在市中心的大规模爆破任务,不但要保证爆破结果(精确),还要控制爆破产生的不良影响。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

Will the BoJ tighten monetary policy
单词facilitate 联想记忆:
There are lots of benefits to studying in a group. You have to be organized. You can't procrastinate. You have to really understand something to be able to explain it out loud to someone else.
As we get closer to relegating 2014 to the history books, your local stock market guru most likely couldn’t be happier to see those books slammed shut.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

The decaying feet, some dating back to 1967, were being 'cleaned up', plumped up and whitened at the 'foul-smelling' plant using bleach and other chemicals, before being prepared for sale.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

我只是忍不住希望,随着《广告狂人》的终结,一个时尚阶段也能终结,在这个阶段,设计师们被困于过去的时代,几乎窒息——至少是困在20世纪60年代(不要忘了,60年代初与50年代末非常相似)至70年代初。
Despite China's rise, an "innovation divide" persists between developed and developing countries amid increasing awareness among policymakers that fostering innovation is crucial to a vibrant, competitive economy.

在4月24日当天,周某带着农药来到重庆荣昌益民技工学校,并把毒药藏在了桌子下面。
波尔图基本与波特酒同义,并同样具有悠久的历史。该城市的历史城区和葡萄酒产区上杜罗已被联合国教科文组织列入世界遗产名录。
它基于针对各商学院及其2013年毕业的学员的调查。
The below are 5 companies that stand out from the rest and are startups to watch in 2014.
Kevin Durant
这部电影是完全的、纯粹的流行天堂,其中不乏独创性和黑色幽默。动作编排恰到好处。某些画面,观影者忍不住想冲出电影院叫来朋友观看。但你并不敢离开位置,你怕错过这绝妙的片段。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


统计局:去年房产成交面积涨幅大 企业投资房产滞后


References

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2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


中国人民银行(PBoC)干预外汇市场由来已久,目的是防止过度波动。不过,交易员们表示,自今年8月以来,这种干预已从国内即期市场(覆盖日常交易)扩大至包括香港的离岸人民币市场,以及在岸和离岸期货市场。
The projects will also cover infrastructure programs such as new connections between Tongzhou and downtown Beijing, sewage and waste water disposal, and energy facilities. Cultural projects will be carried out to provide more employment opportunities, as the construction proceeds on a Universal Studios theme park and a training facility for the National Center for Performing Arts, Lu said.
毋庸置疑,改造比创造容易。任何曾经对着白纸一筹莫展的人都知道这一点。但是,在过去七年里,时尚界对60年代的普遍模仿至少暴露出,这个行业缺乏想象力——不只是对于服装和消费者缺乏想象力,而且对于文化与服装的关系也缺乏想象力。
Dirk Philippa, portfolio manager of Fidelity International’s global property fund, has also cut investments in Hong Kong from a 6-8 per cent overweight two years ago, relative to benchmarks, to a 1 per cent overweight position.
NBS senior statistician Sheng Guoqing attributed the slowdown mainly due to a 1.4-percent decline in food prices, which were down for the first time in 15 years.
张景岫说:“学生本身并不适合创业。”他补充说道,职业院校的学生比大学生更渴望自主创业。
This 1977 file photo shows Apple co-founder Steve Jobs as he introduces the new Apple II in Cupertino, Calif.
WORST GREETING
'In total I've spent about £5,000 in three months on my three girls. One dress cost me $200 and she only wore it twice before she grew out if it - but I don't intend to lower my spending.
1. Jennifer Lawrence

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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网上零售对北京市社会消费品零售额的贡献率达到82.6%。网上零售也促使一些传统商店开展线上销售,北京77家老字号中的13家开展了网上零售业务,商品涉及小吃、鞋等。
10月份,日本生产增长速度突然提升,让决策者对日本经济的实力有了更多希望,或许也可以理解为释放了更多喜忧参半的信号。
Bryant is the first player this season with four or fewer points on 14 or more field goal attempts.
工业部和信息技术部的数据显示,上月新能源汽车的产量为1.61万台,比去年同期大幅上涨了144%。全电动乘用车的产量达到7952台,是去年同期的三倍。政府数据显示,一月份生产的新能源汽车,97%都有资格享受税收优惠政策。

[smɑ:t]

  • Only the first three authors are listed, followed by "et al."
  • 6月一二三线房价齐升温 专家预计下半年调控将再次升级
  • 一线城市楼市库存增长四成 住房投资投机全面退潮


《 佛罗里达乐园》
想知道2013年的最差工作是哪些吗?报社记者以其令人尴尬的特质,取代伐木工人成为今年的最差工作。

BCMJ Guidelines for Authors

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